Coronary disease & ACS

Prognosis of patients with nonspecific electrocardiogram findings in a Tanzanian emergency department

Am Heart JPublished Prospective cohort study

Authors' conclusion

Certain nonspecific ECG findings are associated with increased risk of 30-day mortality.

Study context

Population
Patients presenting with chest pain or shortness of breath to an ED in Moshi, Tanzania, January 2019–January 2023
Participants
1,111 patients
Exposure
Nonspecific electrocardiogram (ECG) findings vs their absence
Outcome
30-day mortality
Follow-up
30 days
Methodological detailssingle-centre, Two independent adjudicators interpreted ECGs using standardized criteria
  • Single-centre
  • Two independent adjudicators interpreted ECGs using standardized criteria

Main finding

As reported in the abstract

30-day mortality by ECG finding
Estimate (95% CI)P value
T-wave inversionsadjusted for age and gender
aOR 1.60(1.19–2.15)
P = 0.002
Resting tachycardiaadjusted for age and gender
aOR 1.57(1.16–2.13)
P = 0.003
Non-sinus rhythmsadjusted for age and gender
aOR 1.93(1.26–2.96)
P = 0.003
ST depressionsadjusted for age and gender
aOR 1.73(1.17–2.56)
P = 0.006
Abnormal ECGvs Normal ECGany abnormal ECG finding
OR 1.53(1.08–2.21)
P = 0.019
Overall 30-day mortality
231 (20.8%)

Observational data: associations, not effects.

Original publication

Prognosis of patients with nonspecific electrocardiogram findings in a Tanzanian emergency department. Am Heart J. Published 19 December 2024. doi:10.1016/j.ahj.2024.11.006

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