Heart failure & cardiomyopathies
Prognostic impact of late gadolinium enhancement at the right ventricular insertion points in non-ischaemic dilated cardiomyopathy
Authors' conclusion
In a large cohort of DCM patients, IP-LGE was associated with similar outcome when compared with LGE- patients and with significant lower risk of ventricular arrhythmias and sudden death when compared with LGE+ cases. Patients with IP&LV-LGE had clinical characteristics and outcomes similar to the rest of LGE+ cases.
Study context
- Population
- Patients with non-ischaemic dilated cardiomyopathy evaluated by CMRIP-LGE in 72 (6%)
- Participants
- 1,165 patients
- Exposure
- IP-LGE vs LGE- vs LGE+ on CMR
- IP-LGEn = 72reference
- Outcome
- Appropriate defibrillator therapies, sustained VT, resuscitated cardiac arrest or sudden death
- Follow-up
- Median 36 months
Methodological detailsmulticentre, observational, consecutive patients
- Multicentre
- Observational
- Consecutive patients
Main finding
As reported in the abstract
Primary endpoint:
- Ventricular arrhythmias
- Sudden death
IP-LGE
0
events
IP-LGE vs LGE-: P = 1 · IP-LGE vs LGE+: P < 0.001
Observational data: associations, not effects.
Secondary outcomes
| Outcome | P value |
|---|---|
| Secondary endpoint (HF hospitalisation, heart transplant, LV assist device implantation, end-stage HF death)LGE- vs IP-LGE · cumulative incidence similar | P = 0.86 |
| Secondary endpoint (HF hospitalisation, heart transplant, LV assist device implantation, end-stage HF death)LGE+ vs IP-LGE · tended to be higher in LGE+ | P = 0.06 |
IP&LV-LGE vs rest of LGE+
- Clinical characteristics and outcomes similar between IP&LV-LGE and the rest of LGE+
Original publication
Prognostic impact of late gadolinium enhancement at the right ventricular insertion points in non-ischaemic dilated cardiomyopathy. Eur Heart J Cardiovasc Imaging. Published 14 June 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →