Prognostic Role of Early Cardiac Magnetic Resonance in Myocardial Infarction With Nonobstructive Coronary Arteries
Authors' conclusion
In MINOCA with early CMR execution, the %LGE and abnormal T2 mapping values were identified as independent predictors of adverse cardiac events at ∼3.0 years of follow-up.
Study context
- Population
- Myocardial infarction with nonobstructive coronary arteries (MINOCA) patients with early cardiac magnetic resonance (CMR), excluding acute myocarditis, takotsubo, cardiomyopathies and other nonischemic etiologies, January 2017 to October 2021437 assessed
- Participants
- 198 patients
- Exposure
- CMR phenotypes: Late gadolinium enhancement (LGE)+/M+ vs LGE-/M+ vs LGE-/M-
- LGE+/M+n = 116
- Outcome
- MACE
- Follow-up
- Mean 33.7 ± 12.0 months
Methodological detailsCMR performed on average 4.8 ± 1.5 days from acute presentation
- CMR performed on average 4.8 ± 1.5 days from acute presentation
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
Independent predictors of major adverse cardiovascular events (MACE) (multivariable Cox regression)
| HR (95% CI) | P value | ||
|---|---|---|---|
| %LGE | 1.123 (1.064–1.185) | P < 0.001 | |
| T2 mapping values | 1.190 (1.145–1.237) | P = 0.001 | |
| 0.512Hazard ratio (log scale) |
- Extension of myocardial damage at CMR significantly greater in patients who developed MACE
Original publication
Prognostic Role of Early Cardiac Magnetic Resonance in Myocardial Infarction With Nonobstructive Coronary Arteries. JACC Cardiovasc Imaging. Published 19 July 2023. doi:10. 1016/ j. jcmg. 2023. 05. 016
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