Characteristics of Premature Myocardial Infarction Among Women With Prior Adverse Pregnancy Outcomes
Authors' conclusion
Among women with premature MIs, 39% had a history of an APO. Women with APO history presented sooner after pregnancy but had similar MI characteristics vs those without APOs.
Study context
- Population
- Women with premature myocardial infarction (MI) (<65 years) referred for left heart catheterization, matched with abstracted pregnancy dataage 49 ± 8 years
- Participants
- 391 women
- Exposure
- Prior APO vs no APO
- APOn = 154
- Outcome
- MI characteristics and epicardial coronary anatomy; time from delivery to MI
Main finding
As reported in the abstract
| Group | Value | Hypertensive disorders of pregnancy | Preeclampsia | Gestational DM | Preterm birth |
|---|---|---|---|---|---|
| APO | 39% | 78 | 35 | 28 | 48 |
APO
Value39%
Hypertensive disorders of pregnancy78
Preeclampsia35
Gestational DM28
Preterm birth48
Observational data: associations, not effects.
Further findings
Time from delivery to MI
P = 0.012
Prevalence of diabetes
P = 0.001
- Time from delivery to MI — Driven by preeclampsia: 17.1 (IQR 12.7-22.4) years
- P = 0.010
Original publication
Characteristics of Premature Myocardial Infarction Among Women With Prior Adverse Pregnancy Outcomes. JACC Adv. Published 19 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →