Heart failure & cardiomyopathies
Prognostic Role of TAPSE to PASP Ratio in Outpatients with Left Ventricular Systolic Dysfunction
Authors' conclusion
TAPSE/PASP was independently associated with mortality or HF events among ambulatory patients with left ventricular systolic dysfunction.
Study context
- Population
- Outpatients with LV systolic dysfunction (EF ≤ 50%) evaluated January–December 2022
- Participants
- 642 outpatients
- Exposure
- TAPSE/PASP tertiles
- Outcome
- Composite of:
- All-cause mortality
- HF events
- Follow-up
- Last available
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Estimated 1-year rate of primary outcome
Adjusted hazard ratio (95% CI)P value
Highest tertilevs Lowest tertilemultivariate analysis
0.61(0.38–0.99)
P = 0.044TAPSE/PASP (continuous, per 0.1 mm/mmHg increase)predominantly driven by higher risk of HF events
0.91(0.84–0.98)
P = 0.009Observational data: associations, not effects.
Further findings
Overall events during follow-up (whole cohort) · median 474 days [IQR 392-507 days]
- Died
- 51 (8.0%)
- CV-related deaths
- 24 (3.8%)
- Composite outcome
- 179 (28.1%)
- Heart failure (HF) events
- 158 (24.8%)
Baseline characteristics with lower TAPSE/PASP
- Higher NYHA class
- P < 0.001
- More signs of congestion
- P = 0.007
- More likely to receive IV furosemide during visit
- P < 0.001
Original publication
Prognostic Role of TAPSE to PASP Ratio in Outpatients with Left Ventricular Systolic Dysfunction. ESC Heart Fail. Published 24 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →