Prognostic significance of subpulmonary left ventricular size and function in patients with a systemic right ventricle
Authors' conclusion
SRV basal diameter, SRV FAC, LV ESDi, and LV FAC are significantly and independently associated with mortality and transplantation in adults with an SRV.
Study context
- Population
- Adults with a systemic RV (Mustard/Senning or congenitally corrected TGA) undergoing transthoracic echocardiography in 2010–18 at a tertiary centre
- Participants
- 180 adults
- Outcome
- All-cause mortality or heart/heart-lung transplantation
- Follow-up
- 4.9 (3.8-5.7) years
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
All-cause mortality or heart/heart-lung transplantation (multivariable Cox, echocardiographic predictors)
Hazard ratio (95% CI)P value
LV ESDi (indexed LV end-systolic diameter)
2.77(1.35–5.68)
P = 0.01LV FAC (fractional area change)
0.7(0.57–0.85)
P = 0.002SRV basal diameter
1.66(1.21–2.29)
P = 0.005SRV FAC
0.65(0.49–0.87)
P = 0.008- Deaths
- 28 (15.6%)
- Heart or heart-lung transplantation
- 4 (2.2%)
Observational data: associations, not effects.
Further findings
Prediction of adverse events (ROC analysis)
- Subpulmonary left ventricular (LV) parameters performed better than systemic right ventricle (SRV) markers
Original publication
Prognostic significance of subpulmonary left ventricular size and function in patients with a systemic right ventricle. Eur Heart J Cardiovasc Imaging. Published 15 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →