Prognostic Value of Coronary Flow Capacity by 82 Rb PET in Patients With Suspected Coronary Artery Disease and Normal Myocardial Perfusion at Semiquantitative Imaging Analysis
Authors' conclusion
In patients with suspected coronary artery disease and normal myocardial perfusion, impaired CFC is associated with a higher risk of cardiac events.
Study context
- Population
- Patients with suspected CAD and normal myocardial perfusion at semiquantitative stress/rest 82Rb PET/CT
- Participants
- 1,967 patients
- Comparison
- Impaired coronary flow capacity (CFC) vs normal CFC
- Outcome
- MI and cardiac death, whichever occurred first
- Follow-up
- Mean 41±27 months
Performance
As reported in the abstract
MI or cardiac death
Events overall
49
Cumulative event rate
2.5%
Annualized event rate
0.5% person-years
CAC score categories and impaired CFC independent predictors of events (multivariable Cox)
P<0.001
Original publication
Prognostic Value of Coronary Flow Capacity by 82 Rb PET in Patients With Suspected Coronary Artery Disease and Normal Myocardial Perfusion at Semiquantitative Imaging Analysis. Circ Cardiovasc Imaging. Published 7 November 2024. doi:10. 1161/ circimaging. 124. 016815
Summarised from the published abstract; every number is checked against it