Coronary disease & ACS

Prognostic Value of Coronary Flow Capacity by 82 Rb PET in Patients With Suspected Coronary Artery Disease and Normal Myocardial Perfusion at Semiquantitative Imaging Analysis

Circ Cardiovasc ImagingPublished Prognostic cohort study

Authors' conclusion

In patients with suspected coronary artery disease and normal myocardial perfusion, impaired CFC is associated with a higher risk of cardiac events.

Study context

Population
Patients with suspected CAD and normal myocardial perfusion at semiquantitative stress/rest 82Rb PET/CT
Participants
1,967 patients
Comparison
Impaired coronary flow capacity (CFC) vs normal CFC
Outcome
MI and cardiac death, whichever occurred first
Follow-up
Mean 41±27 months

Performance

As reported in the abstract

MI or cardiac death

Events overall

49

Cumulative event rate

2.5%

Annualized event rate

0.5% person-years

CAC score categories and impaired CFC independent predictors of events (multivariable Cox)

P<0.001

Original publication

Prognostic Value of Coronary Flow Capacity by 82 Rb PET in Patients With Suspected Coronary Artery Disease and Normal Myocardial Perfusion at Semiquantitative Imaging Analysis. Circ Cardiovasc Imaging. Published 7 November 2024. doi:10.1161/circimaging.124.016815

Summarised from the published abstract; every number is checked against it

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