Coronary disease & ACS

Prognostic value of stress echocardiography assessed by the ABCDE protocol

Eur Heart JPublished Prospective cohort study

Authors' conclusion

ABCDE-SE allows an effective prediction of survival in patients with chronic coronary syndromes.

Study context

Population
All-comers with known or suspected chronic coronary syndromes undergoing clinically indicated ABCDE stress echocardiography, 13 certified laboratories, July 2016–November 2020
Participants
3,574 participants
Exposure
ABCDE-SE score 0 to 5
Outcome
All-cause death
Follow-up
Median 21 months (IQR 13-36)
Methodological detailsmulticentre, international, effectiveness study
  • Multicentre
  • International
  • Effectiveness study

Main finding

As reported in the abstract

Annual mortality rate

Score 0

0.4% person-year

Score 5

2.7% person-year

Deaths during follow-up
73
Global X2, clinical variables
49.5
Global X2 after step A only (P = NS vs clinical variables)
50.7
Global X2 after B-E steps (P < 0.001 vs. step A)
80.6

Observational data: associations, not effects.

Further findings

Rate of abnormal results by step

Step A
16%
Step B
30%
Step C
36%
Step D
28%
Step E
37%

Original publication

Prognostic value of stress echocardiography assessed by the ABCDE protocol. Eur Heart J. Published 27 August 2021. doi:10.1093/eurheartj/ehab493

Summarised from the published abstract; every number is checked against it

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