Arrhythmias & electrophysiology

Prolonged hospitalization after catheter ablation of ventricular tachycardia: Predictors and outcomes

Heart RhythmPublished Retrospective cohort study

Authors' conclusion

Prolonged postablation hospitalization after VT ablation adversely affects outcomes in high-risk patients but not in low-/moderate-risk patients. Procedural factors, such as prolonged ablation duration, are modifiable predictors in low-/moderate-risk populations. Baseline disease severity factors dominate in high-risk groups.

Study context

Population
Patients with structural heart disease undergoing ventricular tachycardia (VT) catheter ablation, January 2022 to October 2024
Participants
318 patient cases
Exposure
Prolonged vs non-prolonged postablation hospitalization
  • Prolonged hospitalizationn = 95
Outcome
Predictors of prolonged hospitalization (>3 days) after VT ablation and their impact on outcomes (mortality, LV assist device implantation, cardiac transplant)

Main finding

As reported in the abstract

Predictors of prolonged hospitalization (postablation LOS > 3 days)
New York Heart Association class > II
OR 3.12; P < 0.001
Moderate/severe right ventricular dysfunction
OR 3.54; P = 0.012
Nonelective ablation
OR 7.42; P < 0.001
Acute procedural complication/pericardial effusion
OR 4.30; P = 0.048
Prolonged postablation hospitalization
95 cases (29.9%)

Observational data: associations, not effects.

Further findings

OutcomeEstimateP value
Death, LV assist device implantation or transplant, by PAINESD stratum (subgroup)High-risk (PAINESD ≥ 17) · Cox survival analysisHR 3.35P = 0.008
Prolonged procedural duration (> 255 minutes) as predictor, by PAINESD stratum (subgroup)Low-/moderate-risk patientsOR 2.89P = 0.010

Death, LV assist device implantation or transplant, by PAINESD stratum (subgroup)

Not associated in low-/moderate-risk patients (PAINESD < 17)

Prolonged procedural duration (> 255 minutes) as predictor, by PAINESD stratum (subgroup)

Not a significant predictor in high-risk patients

Original publication

Prolonged hospitalization after catheter ablation of ventricular tachycardia: Predictors and outcomes. Heart Rhythm. Published 3 June 2025. doi:10.1016/j.hrthm.2025.05.063

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