Prospective Pakistan Registry of Echocardiographic Screening in Asymptomatic Pregnant Women
Authors' conclusion
In a large cohort of pregnant women in Pakistan undergoing routine antenatal echocardiographic screening, almost 4% had structural heart disease. Notably, 2.2% of women had LVSD without active cardiorespiratory symptoms.
Study context
- Population
- Pregnant women without known heart disease or active cardiorespiratory symptoms attending routine antenatal visits, Pakistan, February 2023–March 2024
- Participants
- 15,068 women
- Outcome
- Prevalence of structural heart disease
Methodological detailscross-sectional echocardiographic screening, Standardised limited transthoracic echocardiogram; LVEF by biplane Simpson's method
- Cross-sectional echocardiographic screening
- Standardised limited transthoracic echocardiogram; LVEF by biplane Simpson's method
Main finding
As reported in the abstract
Structural heart disease
Structural heart disease
569
3.8%
LV systolic dysfunction (left ventricular systolic dysfunction (LVSD))
338
2.2%
Valvular heart disease
188
1.2%
Congenital heart disease
68
0.5%
Observational data: associations, not effects.
Further findings
Factors associated with LVSD (multivariable logistic regression)
- Pregnancy-induced hypertension, tachycardia and valvular heart disease associated with LVSD
Original publication
Prospective Pakistan Registry of Echocardiographic Screening in Asymptomatic Pregnant Women. JACC Adv. Published 2 September 2024. doi:10.
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