Cardio-oncology & other

Screening for Hypertensive Disorders of Pregnancy: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

JAMAPublished Systematic review

Authors' conclusion

This review did not identify evidence that any alternative screening strategies for hypertensive disorders of pregnancy were more effective than routine blood pressure measurement at in-person prenatal visits.

Study context

Population
Pregnant or postpartum individuals6 studies (5 trials, 1 nonrandomized)
Participants
10,165 participants
Comparison
Alternative prenatal screening strategies vs usual care
  • Home blood pressure measurementn = 2,521
  • Reduced prenatal visit schedulesn = 5,203
  • Proteinuria screeningn = 2,441
Outcome
Morbidity or mortality, measures of health-related quality of life
Methodological detailstargeted systematic review, no quantitative synthesis
  • Targeted systematic review
  • No quantitative synthesis

Pooled result

As reported in the abstract

Maternal and infant complications
  • No statistically significant differences in maternal and infant complications with alternate strategies vs usual care; estimates imprecise for serious, rare outcomes
  • No quantitative synthesis

Further pooled results

OutcomeHome blood pressure measurementReduced prenatal visit schedulesProteinuria screeningUsual care
Time to diagnosis of a hypertensive disorder of pregnancy (home BP measurement)Not reported in the abstractNot reported in the abstractNot reported in the abstract106.2 daysHome blood pressure measurement, Reduced prenatal visit schedules, Proteinuria screening: not reported in the abstract
  • Time to diagnosis of a hypertensive disorder of pregnancy (home BP measurement): Home BP measurement 104.3 days

Time to diagnosis of a hypertensive disorder of pregnancy (home BP measurement)

Not associated with earlier diagnosis

Incidence of hypertensive disorders of pregnancy (reduced visit schedules)

Incidence not different between groups in 3 trials

Postpartum screening for new-onset hypertensive disorders

No studies addressed screening in the postpartum period

Safety

Harms of screening strategies

No harms of the different screening strategies were identified
  • 1 additional trial (n = 80) addressed harms of home BP measurement only

Original publication

Screening for Hypertensive Disorders of Pregnancy: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. Published 19 September 2023. doi:10.1001/jama.2023.4934

Summarised from the published abstract; every number is checked against it

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