Heart failure & cardiomyopathies
Pulmonary Artery Banding for Cardiomyopathy in Young Children: First Trial in China
Authors' conclusion
Initial results are promising for infants and even toddlers with a dilated left ventricle and limited probability of spontaneous recovery.
Study context
- Population
- Paediatric patients with a significantly dilated LV and preserved RV (dilated cardiomyopathy (DCM))5 boys
- Participants
- 7 patients
- Exposure
- Before vs after surgical pulmonary artery banding (PAB)
- PABn = 7
- Outcome
- LVEF and LV end-diastolic diameter (Z-score), before surgery vs follow-up
- Follow-up
- 348 (200, 629) days
Methodological detailsInitiated in November 2021
- Initiated in November 2021
Main finding
As reported in the abstract
follow-up of 348 (200, 629) days
Median LVEF before surgery → follow-up
27.0 (15.0, 34.0) % → 61.0 (52.0, 68.0) %
P < 0.05
Median LV end-diastolic diameter [Z-score] before surgery → follow-up
43.0 (40.0, 55.0) mm [+9.4 (+7.7, +11.7)] → 33.0 (29.0, 39.0) mm [+1.8 (+1.3, +3.8)]
P < 0.05
Functional regeneration of the LV
5 patients
Observational data: associations, not effects.
Safety
| Outcome | Values |
|---|---|
| Balloon dilation of the PAB to relieve excessively elevated RV pressuresThree of the five patients with functional regeneration | PAB 3 events |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Pulmonary Artery Banding for Cardiomyopathy in Young Children: First Trial in China. ESC Heart Fail. Published 18 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →