Acute cardiac care & resuscitationCohort study

Pulmonary Artery Catheter Use and Mortality in the Cardiac Intensive Care Unit

JACC Heart FailPublished

  • Multicentre registry cohort study
  • annual 2-month snapshots of consecutive CICU admissions
  • adjusted analysis

Authors' conclusion

There is wide variation in the use of PACs that is not fully explained by patient level-factors and appears driven in part by institutional tendency. PAC use was associated with higher survival in cardiac patients with shock presenting to CICUs.

Study context

Population
Consecutive cardiac ICU admissions, Critical Care Cardiology Trials Network, North America, 2017–2021
Participants
13,618 admissions · 34 sites
Exposure
PAC use vs no PAC use
Outcome
In-hospital mortality

Main finding

In-hospital mortality, all shock patients

Odds ratio

0.79

95% CI 0.66–0.96

P = 0.017

PAC vs No PAC
OR 0.79 (95% CI 0.66–0.96); P = 0.017

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeOR (95% CI)P value
Patient-level factors associated with PAC use — Mechanical circulatory support vs No PAC · likelihood of PAC use5.99 (5.15–6.98)P < 0.001
Patient-level factors associated with PAC use — Heart failure vs No PAC · likelihood of PAC use3.33 (2.91–3.81)P < 0.001

Proportion of shock admissions with a PAC, by study center

Varied significantly by center
8% to 73%

Original publication

Pulmonary Artery Catheter Use and Mortality in the Cardiac Intensive Care Unit. JACC Heart Fail. Published 14 June 2023. doi:10.1016/j.jchf.2023.04.007

Summarised from the published abstract; every number is checked against it