Arrhythmias & electrophysiology

Pulmonary Artery Injury Following Endocardial Left Atrial Appendage Occlusion: The Known and Unknown

JACC Clin ElectrophysiolPublished Systematic review of case reports and the FDA MAUDE database

Authors' conclusion

Presentation of PAI after LAAC can occur immediately following the procedure or be delayed.

Study context

Population
Patients with pulmonary artery injury (PAI) after endocardial left atrial appendage closure (LAAC)16 case reports · 20 MAUDE reports
Participants
36 patients
Outcome
PAI after LAAC: characteristics and outcomes

Pooled result

As reported in the abstract

Age, mean ± SD
73.6 ± 8.2 years
CHA2DS2VASC score, median (Q1-Q3)
5 (3-6)
Dual-seal device
75%
Lobular occlusive device
19.4%
Device unspecified
2.8%
Presented postprocedurally within first 24 h
50%
Presented postprocedurally beyond 24 h
38.9%
Presented with cardiac tamponade
61.1%
Presented with cardiac arrest
19.4%
Required surgery with or without antecedent pericardiocentesis
52.8%
Managed with pericardiocentesis
16.7%
Mortality
33.3%

Original publication

Pulmonary Artery Injury Following Endocardial Left Atrial Appendage Occlusion: The Known and Unknown. JACC Clin Electrophysiol. Published 23 October 2024. doi:10.1016/j.jacep.2024.08.016

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