Acute cardiac care & resuscitation
Pulmonary Effective Arterial Elastance by Echocardiography and Mortality in the Cardiac Intensive Care Unit
Authors' conclusion
Noninvasive echocardiographic EPA and RVSP/SBP ratio can be used to incrementally prognosticate among CICU patients, and these parameters predict mortality better than RVSP alone.
Study context
- Population
- Mayo Clinic cardiac intensive care unit (CICU) admissions 2007–2018 with available EPA or right ventricular systolic pressure (RVSP)/SBP
- Participants
- 5,004 admissions
- Exposure
- Higher vs lower EPA and RVSP/SBP ratio
- Outcome
- In-hospital mortality
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Died
7.7%
348 events
Survived
- EPA
- 0.51
- RVSP/SBP ratio
- 0.33
Adjusted odds ratio (95% CI)
EPA per 0.1 higher
1.12(1.09–1.16)
RVSP/SBP per 0.1 higher
1.18(1.11–1.25)
Per 0.1 higher, as printed
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted HR (95% CI) | |
|---|---|---|
| One-year mortalityEPA per 0.1 higher | 1.09 (1.08–1.1) | |
| One-year mortalityRVSP/SBP per 0.1 higher | 1.09 (1.07–1.1) | |
| 0.512Adjusted hazard ratio (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Pulmonary Effective Arterial Elastance by Echocardiography and Mortality in the Cardiac Intensive Care Unit. JACC Adv. Published 28 May 2025. doi:10.
Summarised from the published abstract; every number is checked against it