Acute cardiac care & resuscitation

Clinical Profiles and Outcomes of Adult Congenital Heart Disease Patients in the Cardiac Intensive Care Unit

JACC AdvPublished Retrospective cohort study

Authors' conclusion

ACHD patients in the CICU experience high readmission rates and mortality.

Study context

Population
Cardiac intensive care unit (CICU) admissions at Mayo Clinic, 2007–2018
Participants
12,428 unique CICU admissions
Exposure
Adult congenital heart disease (ACHD) vs non-ACHD CICU admissions
  • ACHDn = 253
Outcome
In-hospital and 1-year mortality
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

ACHD

8.7%

22 of 253

ACHD vs Non-ACHDEstimate (95% CI)P value
In-hospital mortality
adjusted OR 1.76(1.01–2.94)
P = 0.04
1-year mortality
adjusted HR 1.42(1.06–1.89)
P = 0.02

Observational data: associations, not effects.

Further findings

OutcomeValuesP value
1-year survival, by CCD (ACHD)CCD vs No CCDCCD 64.1% · No CCD 87.5%P < 0.001
1-year survival, by CCT (ACHD)CCT vs No CCTCCT 68.5% · No CCT 84.5%P = 0.001

Readmission within 1 year (ACHD hospital survivors)

Hospital survivors readmitted within 1 year
101 (43.9%)

Original publication

Clinical Profiles and Outcomes of Adult Congenital Heart Disease Patients in the Cardiac Intensive Care Unit. JACC Adv. Published 30 April 2025. doi:10.1016/j.jacadv.2025.101710

Summarised from the published abstract; every number is checked against it

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