Acute cardiac care & resuscitation
Pulmonary embolism-related refractory out-of-hospital cardiac arrest and extracorporeal cardiopulmonary resuscitation: Prague OHCA study post hoc analysis
Authors' conclusion
Refractory out-of-hospital cardiac arrest due to PE has a different presentation and inferior outcomes compared to other causes but may represent an important source of organ donations. The ECPR method did not improve patient outcomes.
Study context
- Population
- Patients with refractory OHCA enrolled in the Prague OHCA trial (extracorporeal cardiopulmonary resuscitation (ECPR) vs standard approach)
- Participants
- 256 patients
- Comparison
- PE-related refractory out-of-hospital cardiac arrest (r-OHCA) vs r-OHCA without PE
- PEn = 24
- No PEn = 232reference
- Primary endpoint
- Favourable neurological survival
- Follow-up
- 180 days
Methodological detailspost hoc analysis
- Post hoc analysis
Primary result
As reported in the abstract
Favourable 180-day neurological survival
- PE vs No PE: P = 0.049
- Post hoc analysis
Further findings
Female sex
P < 0.001
Initial non-shockable rhythm
P < 0.001
Median
| Outcome | PE | No PE | P value |
|---|---|---|---|
| pH at admission | 6.83 (IQR 6.75–6.88) | 6.98 (IQR 6.82–7.14) | P < 0.001 |
- Accepted organ donors
- P = 0.04
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Pulmonary embolism-related refractory out-of-hospital cardiac arrest and extracorporeal cardiopulmonary resuscitation: Prague OHCA study post hoc analysis. Eur Heart J Acute Cardiovasc Care. Published 12 May 2023. doi:10.
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