Arrhythmias & electrophysiology
Pulsed-field ablation for atrial fibrillation in patients with cardiac implantable electronic devices
Authors' conclusion
The function and integrity of CIEDs were not compromised by PFA in this study patient cohort; however, transient ventricular pacing inhibition was observed.
Study context
- Population
- Patients with atrial fibrillation and cardiac implantable electronic devices (CIEDs) undergoing pulsed-field ablation (PFA) for pulmonary vein and posterior wall isolationPFA procedures in patients with CIEDs, of 329 PFA procedures in the last 24 months using 4 different PFA systems
- Participants
- 35 patients
- Comparison
- CIED function and integrity before vs after PFA
- Outcome
- Baseline characteristics
Methodological detailsreal-time interrogation of the CIEDs
- Real-time interrogation of the CIEDs
Main finding
As reported in the abstract
Mean age
70.0 ± 8.8 years
Female
40.0%
Further findings
Post-procedural CIED testing (lead impedance, pacing threshold, sensing of intrinsic activities) · after PFA
- No significant changes in lead impedance, pacing threshold, or sensing of intrinsic activities
PFA electrical noise on real-time interrogation
- PFA electrical noise often found when the PFA catheter is in proximity (eg, right pulmonary veins and posterior wall)
Safety
Pacing inhibition due to PFA electrical noise
- Ventricular pacing inhibition in 2 patients
- 2.5 and 3.7 seconds
- Atrial pacing inhibition in 1 patient
- 2.1 seconds
Original publication
Pulsed-field ablation for atrial fibrillation in patients with cardiac implantable electronic devices. Heart Rhythm. Published 27 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →