Arrhythmias & electrophysiology
Pulsed-Field Ablation on Mitral Isthmus in Persistent Atrial Fibrillation: Preliminary Data on Efficacy and Safety
Authors' conclusion
PFA is a feasible and safe ablation approach for mitral isthmus ablation in addition to PVI in patients with persistent AF.
Study context
- Population
- Consecutive patients with persistent atrial fibrillation (AF) undergoing a first ablation procedure with pulsed-field ablation (PFA), November 2021 to September 2022
- Participants
- 45 patients
- Outcome
- Persistent mitral isthmus block at end of procedure (feasibility)
- Follow-up
- End of the procedure
Methodological detailsconsecutive patients, single-group
- Consecutive patients
- Single-group
Main finding
As reported in the abstract
Complete mitral isthmus block
PFA
100%
45 of 45
Observational data: associations, not effects.
Further findings
Recurrence · mean follow-up 107.8 ± 59.5 days
- Recurrence rate
- 20%
Safety
Complications
- Patients with complications
- 3
Reversible, nonfatal coronary spasm
- Coronary spasm cases
- 2 (4.4%)
Original publication
Pulsed-Field Ablation on Mitral Isthmus in Persistent Atrial Fibrillation: Preliminary Data on Efficacy and Safety. JACC Clin Electrophysiol. Published 21 June 2023. doi:10. 1016/ j. jacep. 2023. 03. 021
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