Arrhythmias & electrophysiology

Pulmonary vein isolation (PVI)-only is not enough for all patients with persistent atrial fibrillation (AF): A FLOW-AF subgroup analysis

Heart RhythmPublished Secondary analysis of the FLOW-AF randomised trial

Authors' conclusion

Success rates in no-sources patients receiving PVI only are better than in those with sources randomized to PVI only.

Study context

Population
Patients with nonparoxysmal (persistent/longstanding persistent) AF undergoing redo ablationof 85 enrolled
Participants
47 patients
Comparison
PVI only in patients with vs without electrographic flow (EGF)-identified sources
  • Group 1n = 23reference
  • Group 2n = 24
Primary endpoint
Freedom from recurrent AF (FFAF) after PVI only
Follow-up
1 year
Methodological detailssubgroup analysis, prospective, 4 centres
  • Subgroup analysis
  • Prospective
  • 4 centres

Primary result

As reported in the abstract

FFAF after PVI only · within 1 year

P = 0.018

Further findings

FFAF by electrographic flow consistency (EGFC)

P = 0.011

  • FFAF by electrographic flow consistency (EGFC): high EGFC: 10 of 15; low EGFC: 14 of 31

Original publication

PVI-only is not enough for all patients with persistent AF: A FLOW-AF subgroup analysis. Heart Rhythm. Published 22 October 2024. doi:10.1016/j.hrthm.2024.10.037

Composed by AI from the published abstract and checked against it. How Briefs are made →

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