Early hybrid cardiac rehabilitation in congenital heart disease: the QUALIREHAB trial
Primary result · HRQoL total scoreResult — go to the resultMean difference 3.8 95% CI 0.2–7.3Authors' conclusion
This early hybrid cardiac rehabilitation programme improved HRQoL, body mass index, physical activity, and disease knowledge, in youth with CHD
Study context
- Population
- Adolescent and young adult congenital heart disease (CHD) patients with impaired cardiopulmonary fitness
- Participants
- 142 participants
- Comparison
- Early hybrid cardiac rehabilitation vs standard of care
- Primary endpoint
- Change in health-related quality of life (HRQoL)
- Follow-up
- baseline to 12-month follow-up
Methodological detailsmulticentre
- Multicentre
Primary result
HRQoL total score · 12 months
Mean difference
3.8
95% CI 0.2–7.3
P = 0.038
Interventionvs Standard of care
mean difference 3.8 (95% CI 0.2–7.3); P = 0.038
As reported in the abstract
Secondary outcomes
| Outcome | Mean difference (kg/m²) (95% CI) | P value | |
|---|---|---|---|
| BMIEffect size 0.41 | −0.7 (−1.3 to −0.1) | P = 0.022 | |
| −2−101Difference, kg/m² (linear scale) |
| Outcome | Mean difference (95% CI) | P value | |
|---|---|---|---|
| Level of physical activityEffect size 0.39 | 2.5 (0.1–5) | P = 0.044 | |
| Disease knowledgeEffect size 0.51 | 2.7 (0.8–4.6) | P = 0.007 | |
| −20246Difference (linear scale) |
Original publication
Early hybrid cardiac rehabilitation in congenital heart disease: the QUALIREHAB trial. Eur Heart J. Published 2 March 2024. doi:10.
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