Coronary disease & ACS

Quality of care and long-term survival after ST-elevation myocardial infarction in adults with cancer

Eur Heart J Qual Care Clin OutcomesPublished nationally-linked cohort

Authors' conclusion

Quality of care is closely associated with short- and long-term survival among STEMI patients with cancer. Improving quality of care may save hundreds to thousands of lives in the shorter and longer term.

Study context

Population
ST-elevation myocardial infarction (STEMI) patients with cancer, UK Myocardial Infarction National Audit Project and UK national Hospital Episode Statistics Admitted Patient Care registries (January 2005-March 2019)STEMI indexed admissions with cancer
Participants
6,787 patients
Exposure
Low care quality compared to patients with optimum care
  • Optimum caren = 4,340reference
  • Intermediate caren = 1,320
  • Low care qualityn = 1,127
Outcome
Death
Follow-up
30 days, 1 year, 5 years

Main finding

As reported in the abstract

low care quality vs optimum careHazard ratio (95% CI)
30 days
7.0(5.7–8.7)
1 year
4.0(3.6–4.4)
5 years
2.6(2.4–2.8)

Observational data: associations, not effects.

Further findings

Women

Median

OutcomeOptimum careIntermediate careLow care quality
Age72.8 (IQR 65.1–79.6)75.5 (IQR 67.9–82.1)78.2 (IQR 69.2–84.7)

Number of patients who would survive nationally if they received optimal care (relative survival analysis) · 30 days, 1 year, 5 years

30 days
84 (95% CI 67-102)
1 year
508 (95% CI 468-548)
5 years
1096 (95% CI 1034-1158)

Regional variation

The association between care quality and survival was more profound in the Northwest and Northeast regions

Original publication

Quality of care and long-term survival after ST-elevation myocardial infarction in adults with cancer. Eur Heart J Qual Care Clin Outcomes. Published 27 February 2025. doi:10.1093/ehjqcco/qcaf004

Summarised from the published abstract; every number is checked against it

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