Trends in ST-elevation myocardial infarction hospitalization among young adults: a binational analysis
Authors' conclusion
The demographics of young STEMI patients have temporally changed in the UK and USA, with increased proportions of females and ethnic minorities. There was a significant increase in the frequency of diabetes mellitus over the respective time periods in both countries.
Study context
- Population
- STEMI patients aged ≤50, United Kingdom (UK) and US
- Participants
- 32,719 vs 238,952
- Exposure
- Temporal trends: later vs earlier period
- UK (Myocardial Ischemia National Audit Project (MINAP))n = 32,719
- United States of America (USA) (National Inpatient Sample (NIS))n = 238,952
- Outcome
- Temporal trends in demographics, management and mortality
Methodological detailsbinational, national registry and administrative database
- Binational
- National registry and administrative database
Main finding
As reported in the abstract
Odds ratio (95% CI)
UK 2016-2017 vs UK 2010-2012adjusted all-cause mortality; no difference
1.21(0.60–2.40)
USA 2016-2018 vs USA 2010-2012adjusted all-cause mortality; decrease
0.84(0.79–0.90)
- Proportion of females, UK: 2010-2012 to 2016-2017
- 15.6% to 17.6%
- Proportion of females, USA: 2010-2012 to 2016-2018
- 22.8% to 23.1%
- Proportion of white patients, UK: 2010 to 2017
- 86.7% to 79.1%
- Proportion of white patients, USA: 2010 to 2017
- 72.1% to 67.1%
- Invasive coronary angiography, UK: 2010-2012 to 2016-2017
- 89.0% to 94.3%
- Invasive coronary angiography, USA: 2010-2012 to 2016-2018
- 88.9% to 86.2%
Observational data: associations, not effects.
Original publication
Trends in ST-elevation myocardial infarction hospitalization among young adults: a binational analysis. Eur Heart J Qual Care Clin Outcomes. Published 13 June 2023. doi:10.
Summarised from the published abstract; every number is checked against it