Acute cardiac care & resuscitation

Quality of life after out-of-hospital cardiac arrest: a TOMAHAWK sub-study

Eur Heart J Acute Cardiovasc CarePublished Secondary analysis of the TOMAHAWK randomised trial

Authors' conclusion

OHCA survivors of the TOMAHAWK trial rated their HRQoL 6 and 12 months after the event as relatively good, but there were notable differences between women and men and between younger and elderly patients. The angiography strategy did not affect HRQoL.

Study context

Population
Resuscitated out-of-hospital cardiac arrest (OHCA) survivors without ST-segment elevationssurvivors completing 6M-FU and 12M-FU
Participants
169 survivors
Comparison
Immediate vs delayed/selective coronary angiography
Primary endpoint
Health-related quality of life (HRQoL) by EuroQoL-5D-3L (EQ-VAS 0–100, worst to best, and five dimensions)
Follow-up
6 and 12 months

Primary result

As reported in the abstract

EQ-VAS score · 6M-FU

Immediate angiography

70

± 21

Delayed/selective angiography

74

± 18

Further findings

Problems with usual activities and self-care · 6M-FU · most problems with usual activities, fewest with self-care

Usual activities

Self-care

OutcomeImmediate angiographyDelayed/selective angiography
EQ-VAS score · 12M-FU72 ± 19— not stated in the abstract

— not stated in the abstract

EQ-VAS score · 12M-FU

No relevant differences between groups

EQ-5D dimensions by sex

Women reported more problems than men in all five dimensions

EQ-5D dimensions by age

Elderly (≥65 years) more likely than younger survivors to report limitations in mobility, self-care, usual activities and pain/discomfort

Original publication

Quality of life after out-of-hospital cardiac arrest: a TOMAHAWK sub-study. Eur Heart J Acute Cardiovasc Care. Published 25 June 2025. doi:10.1093/ehjacc/zuaf093

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