Arrhythmias & electrophysiology

Quantitative analysis reveals influencing factors to facilitate successful anodal-ring capture in left bundle branch pacing

EuropacePublished Observational study

Authors' conclusion

This study elucidated the factors affecting the success likelihood of LBBP-ARC.

Study context

Population
Patients receiving left bundle branch pacing (LBBP) with intraoperative anodal-ring capture (ARC) testing
Participants
105 patients
Exposure
LBBP with ARC vs LBBP without ARC
  • LBBP-ARCn = 65
Outcome
Factors influencing ARC implementation

Main finding

As reported in the abstract

ARC success
GroupValueAverage ARC output
LBBP-ARC62%3.1 V/0.5 ms

LBBP-ARC

Value62%
Average ARC output3.1 V/0.5 ms

Observational data: associations, not effects.

Further findings

Further shortening of stimulus-to-QRS duration (stim-QRSd) with ARC

ARC further shortened stim-QRSd
13.1 ± 7.5 ms

Unipolar-ring (cathodal) threshold and R-wave sensing

Better unipolar-ring (cathodal) threshold and R-wave sensing in LBBP-ARC group, indicating critical role of ring-septum contact

Lead-tip site distribution

Longer corrected longit-dist and shorter corrected lat-dist positively correlated with higher ARC success likelihood

Original publication

Quantitative analysis reveals influencing factors to facilitate successful anodal-ring capture in left bundle branch pacing. Europace. Published 20 June 2023. doi:10.1093/europace/euad172

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