Quantitative coronary CT analysis reveals non-calcified atherosclerotic plaques in women with a history of pre-eclampsia
Main finding · Noncalcified plaque volume (among women with plaques)Result — go to the resultbeta 0.62 95% CI 0.17–1.07Authors' conclusion
Women with a history of preeclampsia have coronary plaques with larger noncalcified plaque volume compared to unaffected women, driven by larger fibrous and fibrous fatty plaque volumes, independent of total plaque volume.
Study context
- Population
- Women aged 45–55 years undergoing coronary CT angiography
- Participants
- 138 vs 390
- Exposure
- History of pre-eclampsia vs no history of pre-eclampsia
- Preeclampsian = 138
- Referencen = 390reference
- Outcome
- Coronary plaque characteristics: total, calcified and noncalcified plaque volumes (quantitative coronary computed tomography angiography (CCTA))
Main finding
As reported in the abstract
Noncalcified plaque volume (among women with plaques)
beta
0.62
95% CI 0.17–1.07
Observational data: associations, not effects.
Further findings
| Outcome | Beta (95% CI) |
|---|---|
| Fibrous and fibrous fatty plaque volume (among women with plaques)Preeclampsia vs Reference · fibrous plaque | 0.71 (0.26–1.15) |
| Fibrous and fibrous fatty plaque volume (among women with plaques)Preeclampsia vs Reference · fibrous fatty plaque | 0.52 (0.01–1.03) |
Original publication
Quantitative coronary CT analysis reveals non-calcified atherosclerotic plaques in women with a history of pre-eclampsia. Eur J Prev Cardiol. Published 18 November 2025. doi:10. 1093/ eurjpc/ zwaf713
Summarised from the published abstract; every number is checked against it