Race- and Sex-Specific Age at Which Coronary Artery Calcium Becomes Detectable Among Young Adults
Authors' conclusion
The age at which CAC becomes detectable in young adults varies substantially by race, sex, and the number of ASCVD risk factors. Earlier initiation of CAC scans may be indicated in select subgroups at greater risk of premature atherosclerosis.
Study context
- Population
- Participants aged 30 to 50 years from the coronary artery calcium (CAC) Consortium and the CARDIA (Coronary Artery Risk Development in Young Adults) studymean age, 43.3±4.7years, 66.9% men, and 87.5% White
- Participants
- 17,285 participants
- Exposure
- Sex- and race-specific multivariable logistic regression models to predict the probability of CAC >0
- Outcome
- Prevalence of CAC >0
Main finding
As reported in the abstract
Participants with CAC >0
30.1%
Observational data: associations, not effects.
Further findings
Estimated age at which CAC became detectable, with 2 ASCVD risk factors
- Estimated age at which CAC became detectable, with 2 atherosclerotic cardiovascular disease (ASCVD) risk factors: minimum testing yield of 25%
Probability of CAC >0 by sex and race
- Higher among men than women and White compared with Black individuals
Original publication
Race- and Sex-Specific Age at Which Coronary Artery Calcium Becomes Detectable Among Young Adults. Circ Cardiovasc Imaging. Published 3 March 2025. doi:10.
Summarised from the published abstract; every number is checked against it