Arrhythmias & electrophysiology

Rate-Dependent Pacemap Matching in Scar-Related Ventricular Tachycardia: Impact of "TR Fusion" Phenomenon

JACC Clin ElectrophysiolPublished Mechanistic study

Authors' conclusion

The rate of pacemapping can significantly alter morphologic score matching, with the most optimal match observed closest to VT CL. The onset of QRS complex morphology is influenced by superimposition of the preceding T-wave at faster rates, resulting in an underrecognized TR fusion phenomenon that may confound epicardial electrocardiographic criteria predicated upon the initial QRS slope and vector.

Study context

Population
Patients undergoing scar-related ventricular tachycardia (VT) ablation
Participants
40 patients269 pacemapping (PMs)
Comparison
Pacemapping at cycle lengths (CLs) of 600 ms, 500 ms, 400 ms, 300 ms and VT CL
Outcome
Variability in PM score matching at different pacing rates

Main finding

As reported in the abstract

PM score

PM score improved at rates closer to VT; median difference between lowest and highest PM scores at a given site (Q1-Q3: 4%-10%; range: 0%-33%)

6%

Sites developing pseudo delta wave at faster PM rates

32%

Endocardial pacing sites fulfilling epicardial criteria at faster PM rates

69%

Original publication

Rate-Dependent Pacemap Matching in Scar-Related Ventricular Tachycardia: Impact of "TR Fusion" Phenomenon. JACC Clin Electrophysiol. Published 11 September 2024. doi:10.1016/j.jacep.2024.06.034

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