Coronary disease & ACS

Rationale and design of the multicentric randomized EVAOLD trial: Evaluation of a strategy guided by imaging versus routine invasive strategy in elderly patients with ischemia

Am Heart JPublished Rationale and design of a randomised controlled trial

Study context

Population
NSTEMI patients ≥80 years of ageplanned sample size 1,756
Planned comparison
Selective invasive strategy guided by ischaemia stress imaging vs routine invasive strategy
Primary endpoint
Major Adverse Cardiac and Cerebrovascular Events (MACCE):
  • All-cause death
  • Nonfatal MI
  • Nonfatal stroke
Follow-up
1 year
Methodological detailsmulticentre, prospective, open-label, 2 parallel arms, non-inferiority, Geriatric assessment and cost-effectiveness analysis also planned
  • Multicentre
  • Prospective
  • Open-label
  • 2 parallel arms
  • Non-inferiority
  • Geriatric assessment and cost-effectiveness analysis also planned

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Rationale and design of the multicentric randomized EVAOLD trial: Evaluation of a strategy guided by imaging versus routine invasive strategy in elderly patients with ischemia. Am Heart J. Published 23 October 2024. doi:10.1016/j.ahj.2024.10.013

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