Heart failure & cardiomyopathies

Real-Time Pulmonary Artery Pressure Monitoring in Heart Failure Patients: An Updated Cost-Effectiveness Analysis

ESC Heart FailPublished Cost-effectiveness analysis

Authors' conclusion

Our model suggests that CardioMEMS is likely to be cost-effective in the United Kingdom, at the currently considered thresholds of £20 000-30 000/QALY.

Study context

Population
Patients with persistent NYHA class III symptoms and ≥1 heart failure (HF) hospitalization within 12 months
Comparison
Pulmonary artery pressure (PAP)-guided HF therapy vs usual care
Outcome
Incremental cost per QALY gained (ICER)
Follow-up
10 years
Methodological detailsMarkov model, 10-year time horizon, UK
  • Markov model
  • 10-year time horizon
  • UK

Main finding

As reported in the abstract

10-year time horizon

Incremental cost

6337 £

PAP-guided

Incremental quality-adjusted life years (QALYs)

0.32 QALYs

PAP-guided

Usual care

Cost
£22 770
QALYs
2.62

PAP-guided

Cost
£29 107
QALYs
2.94

Cost

Usual care£22 770
PAP-guided£29 107

QALYs

Usual care2.62
PAP-guided2.94
Incremental cost-effectiveness ratio (ICER) (incremental cost per QALY gained)
£19 761/QALY

Further findings

ICER, scenario analyses (incl. real-world data)

ICER range from dominant to
£27 910/QALY

Probabilistic sensitivity analysis

Probability CardioMEMS cost-effective at £30 000/QALY threshold
81.9%

Original publication

Real-Time Pulmonary Artery Pressure Monitoring in Heart Failure Patients: An Updated Cost-Effectiveness Analysis. ESC Heart Fail. Published 17 August 2023. doi:10.1002/ehf2.14496

Composed by AI from the published abstract and checked against it. How Briefs are made →

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