Acute cardiac care & resuscitation
Reasons for death in patients receiving extracorporeal cardiopulmonary resuscitation (ECPR) for refractory out-of-hospital cardiac arrest
Authors' conclusion
Refractory shock was the leading cause of death among our cohort of ECPR patients, followed closely by neurological complications, while other causes were rare.
Study context
- Population
- Patients who received ECPR following out-of-hospital cardiac arrest (OHCA)underwent ECPR, of 1,219 OHCA patients admitted, 152 died during index hospitalization
- Participants
- 210 patients
Primary result
As reported in the abstract
In-hospital death among ECPR patients · index hospitalization
Patients who died during index hospitalization, among the 210 who underwent ECPR
152
72.3%
Further findings
Primary cause of death, among the 152 deceased patients
- Refractory shock
- 75/152 patients, 49.3%
- Neurological injury
- 69/152 patients, 45.3%
- Rearrest
- 7/152 patients, 4.6%
- Comorbidities
- 1/152 patients, 0.6%
Characteristics of deceased patients
- Median age of deceased patients
- 57 years
- Male, among deceased patients
- 80.9%
- Median time to ECPR initiation
- 62 min (IQR: 53-72)
Interrater agreement (Fleiss' kappa)
- Interrater agreement
- 0.81
Original publication
Reasons for death in patients receiving ECPR for refractory out-of-hospital cardiac arrest. Resuscitation. Published 16 April 2025. doi:10.
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