Arrhythmias & electrophysiology
Reduction of moderate to severe tricuspid regurgitation after catheter ablation for atrial fibrillation
Authors' conclusion
In patients with AF with moderate to severe TR, more than two-thirds of patients experienced reduced TR severity, with notable improvements in echocardiographic parameters. Sinus rhythm maintenance was associated with significant TR reduction.
Study context
- Population
- Patients with drug-refractory AF and moderate to severe secondary tricuspid regurgitation (TR) undergoing AF catheter ablation70 analysed
- Participants
- 106 patients
- Outcome
- At least one grade TR reduction
- Follow-up
- 1 year
Methodological detailssingle-centre ablation registry
- Single-centre ablation registry
Main finding
As reported in the abstract
≥1 grade TR reduction · 1-year assessment
Primary outcome achieved, 53 patients
75.7%
Moderate TR
73.6%
Severe TR
82.4%
Observational data: associations, not effects.
Further findings
Determinant of TR reduction: sinus rhythm maintenance (multivariate)
| OR (95% CI) | ||
|---|---|---|
| Sinus rhythm maintenanceMost significant determinant | 8.3 (1.8–37.4) | |
| 0.050.21520Odds ratio (log scale) |
Echocardiographic parameters · 1 year
- Vena contracta, significant decrease
- 6.1→3.2 mm
- Tricuspid annular diameter, significant decrease
- 37.3→32.6 mm
Sinus rhythm maintenance · 1 year
- AF recurrence within 1 year, patients
- 25
- Sinus rhythm finally maintained with medical treatment, 56 patients
- 80%
- With TR reduction
- 87%
- Without TR reduction
- 59%
Original publication
Reduction of moderate to severe tricuspid regurgitation after catheter ablation for atrial fibrillation. Heart. Published 25 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →