Arrhythmias & electrophysiology
Need for cardiac implantable electronic devices and long-term follow-up in recipients of orthotopic heart transplants
Authors' conclusion
The risk of pacemaker implantation increases progressively, while ICD implantation is rare. Donor age is the predominant risk factor for subsequent heart block. Early sinus node dysfunction requiring permanent pacing is rare.
Study context
- Population
- Adult recipients of orthotopic heart transplants with bicaval anastomosis, 1991–2017
- Participants
- 399 recipients
- Outcome
- Freedom from pacemaker or ICD implantation
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
CIED implantation · follow-up 0-30 years; median 11 years
| Group | Value | Pacemakers for sinus node dysfunction | Pacemakers for high-grade heart block | Implantable cardioverter-defibrillator (ICDs) for primary prevention of SCD |
|---|---|---|---|---|
| Cardiac implantable electronic device (CIED) | 8% | 11 (35%) | 17 (55%) | 3 (10%) |
Cardiac implantable electronic device (CIED)
Value8%
Pacemakers for sinus node dysfunction11 (35%)
Pacemakers for high-grade heart block17 (55%)
Implantable cardioverter-defibrillator (ICDs) for primary prevention of SCD3 (10%)
Observational data: associations, not effects.
Secondary outcomes
Survival after transplantation (all-cause mortality)
P < 0.01
Donor age, pacemaker for heart block
- Recipients receiving pacemakers for heart block more likely to receive older donor hearts
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Need for cardiac implantable electronic devices and long-term follow-up in recipients of orthotopic heart transplants. Heart Rhythm. Published 24 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →