Regional and ethnic differences among patients with heart failure in Asia: the Asian sudden cardiac death in heart failure registry
Authors' conclusion
These first prospective multi-national data from Asia highlight the significant heterogeneity among Asian patients with stable HF, and the important influence of both ethnicity and regional income level on patient characteristics.
Study context
- Population
- Patients with stable heart failure (HF) and reduced EF (≤40%) from 11 Asian regions
- Participants
- 5,276 patients · 11 Asian regions
- Exposure
- Ethnic groups and regions among Asian HF patients
- Outcome
- CAD by ethnicity
Methodological detailsmultinational, 11 Asian regions
- Multinational
- 11 Asian regions
Main finding
As reported in the abstract
Each group vs chineseEstimate (95% CI)
Malays
adjusted OR 1.97(1.63–2.38)
Indians
OR 1.44(1.24–1.68)
Koreans
OR 0.38(0.29–0.50)
Japanese
OR 0.44(0.36–0.55)
- Coronary Artery Disease (CAD) prevalence, Southeast vs Northeast Asians
- 58.8 vs. 38.2%
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted odds (95% CI) |
|---|---|
| Hypertension and diabetes, high- vs low-income regions, by ethnicityIndians, high-income regions vs Indians, low-income regions · hypertension · Significant interaction between ethnicity and region | 3.95 (2.51–6.21) |
| Hypertension and diabetes, high- vs low-income regions, by ethnicityIndians, high-income regions vs Indians, low-income regions · diabetes · Significant interaction between ethnicity and region | 4.91 (3.07–7.87) |
| Hypertension and diabetes, high- vs low-income regions, by ethnicityMalays, high-income regions vs Malays, low-income regions · hypertension · Significant interaction between ethnicity and region | 2.60 (1.66–4.06) |
| Hypertension and diabetes, high- vs low-income regions, by ethnicityMalays, high-income regions vs Malays, low-income regions · diabetes · Significant interaction between ethnicity and region | 2.62 (1.73–3.97) |
Baseline characteristics
- Mean age (years)
- 59.6 ± 13.1
- Men
- 78.2%
- Mean BMI (kg/m²)
- 24.9 ± 5.1
- Two or more comorbidities
- 64%
- Hypertension
- 51.9%
- CAD
- 50.2%
- Diabetes
- 40.4%
Hypertension and diabetes prevalence by region
- Southeast Asians (hypertension, diabetes)
- 64.2 and 49.3%
- High-income regions (hypertension, diabetes)
- 59.7 and 46.2%
- Highest in Southeast Asians and high-income regions
Original publication
Regional and ethnic differences among patients with heart failure in Asia: the Asian sudden cardiac death in heart failure registry. Eur Heart J. Published 7 August 2016. doi:10.
Summarised from the published abstract; every number is checked against it