Relation of Myocardial Dysfunction to Biomarkers, COVID-19 Severity and All-Cause Mortality
Main finding · All-cause deathResult — go to the resultHazard ratio 4.007 95% CI 11.347–11.919Authors' conclusion
GLS, GCS and GRS are significantly related to myocardial dysfunction in patients with COVID-19. Worsening GCS poses an increased risk of death in COVID-19.
Study context
- Population
- Patients with COVID-1919 deaths
- Participants
- 220 patients
- Exposure
- Global longitudinal strain (GLS), global circumferential strain (GCS) and global radial strain (GRS) (speckle-tracking echocardiography) in relation to biomarkers, COVID-19 severity and all-cause mortality
- Mildn = 127
- Moderaten = 43
- Severe/criticaln = 50
- Outcome
- All-cause mortality
- Follow-up
- Average 11 days
Main finding
All-cause death
Hazard ratio
4.007
95% CI 11.347–11.919
As reported in the abstract
Observational data: associations, not effects.
Further findings
Correlation of GLS, GCS, GRS with blood urea nitrogen (BUN)
- GLS vs BUN r
- 0.206
- GCS vs BUN r
- 0.221
- GRS vs BUN r
- 0.355
Correlation of Cardiac troponin I (cTnI) with GLS and GCS
- cTnI vs GLS r
- 0.240
- cTnI vs GCS r
- 0.324
Original publication
Relation of Myocardial Dysfunction to Biomarkers, COVID-19 Severity and All-Cause Mortality. ESC Heart Fail. Published 29 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →