Acute cardiac care & resuscitation
Resource utilization associated with extracorporeal membrane oxygenation vs. microaxial flow pump for infarct-related cardiogenic shock
Authors' conclusion
Microaxial flow pump was associated with lower resource utilization compared with VA-ECMO. Resource utilization should be incorporated in prospective RCTs and taken into account when considering these devices.
Study context
- Population
- Patients with infarct-related cardiogenic shock treated with microaxial flow pump or venoarterial extracorporeal membrane oxygenation (VA-ECMO)12 retrospective cohorts · microaxial flow pump 92,262 · VA-ECMO 16,474
- Participants
- 92,262 vs 16,474
- Comparison
- Microaxial flow pump vs VA-ECMO
- Microaxial flow pumpn = 92,262
- VA-ECMOn = 16,474
- Outcome
- ICU LOS, hospital LOS, in-hospital costs and discharge destination
Methodological detailsrandom-effect models, PRISMA-2020 guideline, Newcastle-Ottawa-Scale risk-of-bias assessment, 12 retrospective cohorts
- Random-effect models
- PRISMA-2020 guideline
- Newcastle-Ottawa-Scale risk-of-bias assessment
- 12 retrospective cohorts
Pooled result
As reported in the abstract
Microaxial flow pump vs VA-ECMOMD, days (95% CI)
Hospital LOS; favourable for the microaxial flow pump
−5.3(−6.6 to −4.1)
- In-hospital costs; favourable for the microaxial flow pump
- MD -$113 983 (95% CI -$143 153, -$84 812)
- Microaxial flow pump survivors 45% more likely to be discharged home (95% CI)
- 1.28-1.64
- Intensive care unit (ICU) length of stay (LOS) (one study): MD in favour of the microaxial flow pump
- 10 days
Further pooled results
Averaged rate
| Outcome | Microaxial flow pump | VA-ECMO |
|---|---|---|
| In-hospital mortality (secondary)Confounding by indication is an inherent limitation | 44% | 57% |
Original publication
Resource utilization associated with extracorporeal membrane oxygenation vs. microaxial flow pump for infarct-related cardiogenic shock. Eur Heart J Acute Cardiovasc Care. Published 12 February 2025. doi:10.
Summarised from the published abstract; every number is checked against it