Valvular & structural heart disease
Restoration of Life Expectancy After Transcatheter Edge-to-Edge Mitral Valve Repair
Authors' conclusion
Mitral TEER in patients 80 to 89 years of age is able to restore predicted life expectancy in PMR, whereas in SMR with sustained procedural success, high RS estimates were observed.
Study context
- Population
- Consecutive transcatheter edge-to-edge repair (TEER) patients aged 60 to 89 years in the MitraSwiss registry, enrolled 2011–2018
- Participants
- 1,140 patients
- Exposure
- TEER survival vs expected survival in age-, sex- and calendar period-matched general population
- Outcome
- Survival and relative survival (RS) after TEER
- Follow-up
- 5 years
Methodological detailsrelative survival analysis, consecutive patients
- Relative survival analysis
- Consecutive patients
Main finding
As reported in the abstract
5-year survival and RS after TEER
| Group | 5-year survival | Relative survival (RS) |
|---|---|---|
| TEER | 59.3% (95% CI: 54.9%-63.4%) | 80.5% (95% CI: 74.6%-86.0%) |
TEER
5-year survival59.3% (95% CI: 54.9%-63.4%)
Relative survival (RS)80.5% (95% CI: 74.6%-86.0%)
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Relative survival, patients 80 to 89 years of age (n = 579) | 80 to 89 years of age 93.0% (95% CI 83.3%–101.9%) |
Percent
PMR
91.1%(95% CI 82.5%–98.6%)
SMR
71.5%(95% CI 63.0%–79.3%)
Percent
PMR
100%(95% CI 87.9%–110.7%)
SMR
90.6%(95% CI 71.3%–107.3%)
- Primary mitral regurgitation (PMR): restoration of predicted life expectancy
- Secondary mitral regurgitation (SMR): with sustained procedural success
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Restoration of Life Expectancy After Transcatheter Edge-to-Edge Mitral Valve Repair. JACC Cardiovasc Interv. Published 23 August 2023. doi:10.
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