Pulmonary vascular disease & thromboembolism

Revisiting the Open Vein Hypothesis to Reduce the Postthrombotic Syndrome: Implications for Multidisciplinary Care and Research: A Scientific Statement From the American Heart Association

CirculationPublished Scientific statement

Recommendations

As issued by the authors

  1. Highlights historical fundamentals of the open vein hypothesis and new research insights into the pathophysiological factors driving postthrombotic syndrome

  2. Discusses advantages and disadvantages of imaging modalities for DVT used in clinical practice, including the potential to depict thrombus chronicity and status of vein wall injury

  3. Proposes measures to develop integrated multidisciplinary care for DVT focused on the reduction of postthrombotic syndrome

  4. Identifies priority areas and questions for further research

Original publication

Revisiting the Open Vein Hypothesis to Reduce the Postthrombotic Syndrome: Implications for Multidisciplinary Care and Research: A Scientific Statement From the American Heart Association. Circulation. Published 13 May 2025. doi:10.1161/cir.0000000000001330

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