Right atrial dysfunction is associated with atrial arrhythmias in adults with repaired tetralogy of fallot
An erratum to this article was published (Am Heart J, Sep 2024 ↗)
Main finding · New-onset atrial arrhythmiasResult — go to the resultAdjusted hazard ratio 0.95 95% CI 0.93–0.97Authors' conclusion
RA strain indices can identify patients at risk for atrial arrhythmias
Study context
- Population
- Adults with repaired tetralogy of Fallot (TOF) and no prior atrial arrhythmias
- Participants
- 426 adults
- Outcome
- New-onset atrial arrhythmia (AF, atrial flutter/atrial tachycardia) in relation to RA reservoir strain
Main finding
New-onset atrial arrhythmias
Adjusted hazard ratio
0.95
95% CI 0.93–0.97
RA reservoir strain
adjusted HR 0.95 (95% CI 0.93–0.97)
As reported in the abstract
- New-onset atrial arrhythmias
- 73 (17%)
- Atrial flutter/tachycardia
- 42
- AF
- 31
- Annual incidence
- 1.9%
Observational data: associations, not effects.
Further findings
Recurrent atrial arrhythmias (among 73 with new-onset)
| Adjusted HR (95% CI) | ||
|---|---|---|
| RA reservoir strainAfter multivariable adjustment | 0.92 (0.88–0.96) | |
| 0.512Adjusted hazard ratio (log scale) |
- Recurrent atrial arrhythmias (among 73 with new-onset) — Recurrent atrial arrhythmia
- 41 (56%)
- Recurrent atrial arrhythmias (among 73 with new-onset) — Atrial flutter/tachycardia
- 18
- Recurrent atrial arrhythmias (among 73 with new-onset) — AF
- 23
- Recurrent atrial arrhythmias (among 73 with new-onset) — Annual incidence
- 11.2%
Right atrial (RA) strain at baseline (mean ± SD)
- Reservoir strain
- 34 ± 11%
- Conduit strain
- 20 ± 9%
- Booster strain
- 15 ± 12%
Original publication
Right atrial dysfunction is associated with atrial arrhythmias in adults with repaired tetralogy of fallot. Am Heart J. Published 3 June 2023. doi:10.
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