Multidetector Computed Tomography Assessment of Anatomical Ventricular Tachycardia Isthmuses in Repaired Tetralogy of Fallot
Authors' conclusion
MDCT identifies anatomical structures relevant to catheter ablation for repaired TOF. Wall thickness at commonly targeted anatomical VT isthmuses is associated with functional isthmus properties and increased thermal energy delivery.
Study context
- Population
- Repaired Tetralogy of Fallot (TOF) patients undergoing multidetector computed tomography (MDCT) before transcatheter pulmonary valve placement35 MDCT–electroanatomical map pairs
- Participants
- 61 patients
- Exposure
- Blocked isthmus vs Slow conduction vs Normal conduction
- Outcome
- Impact of MDCT in evaluation of sustained monomorphic ventricular tachycardia (VT) (anatomical VT isthmus dimensions)
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
MDCT wall thickness by functional isthmus property
P < 0.001
Observational data: associations, not effects.
Further findings
Calcification corresponding to patch material
- Present
- 46 (75%)
Coronary findings
- Large conal branch
- 6 (10%)
- Major coronary anomaly
- 3 (5%)
Median ablation lesion distance to coronary artery
- Right vs left coronary artery
- 10 mm vs 15 mm; P = 0.01
- Lesion-to-coronary distance <5 mm
- 3 patients
Original publication
Multidetector Computed Tomography Assessment of Anatomical Ventricular Tachycardia Isthmuses in Repaired Tetralogy of Fallot. JACC Clin Electrophysiol. Published 6 March 2024. doi:10.
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