Valvular & structural heart diseaseCohort study
Right Heart Reverse Remodeling and Prosthetic Valve Function After Transcatheter vs Surgical Pulmonary Valve Replacement
- Matched cohort study
Authors' conclusion
These data suggest a more favorable right heart outcome after TPVR. However, the risk of prosthetic valve endocarditis and prosthetic valve dysfunction remains a major concern.
Study context
- Population
- Patients undergoing pulmonary valve replacement for congenital heart lesionsmatched 1:2
- Participants
- 64 vs 128
- Exposure
- Transcatheter pulmonary valve replacement (TPVR) vs surgical pulmonary valve replacement (SPVR)
- TPVRn = 64
- SPVRn = 128reference
- Outcome
- Right heart reverse remodeling, pulmonary valve gradients and prosthetic valve dysfunction
Main finding
As reported in the abstract
Right heart reverse remodeling · 1 and 3 years
- Greater improvement in RA reservoir strain and RV global longitudinal strain with TPVR
Observational data: associations, not effects.
Further findings
Pulmonary valve mean gradients · 9 years
- Similar in both groups
Pulmonary valve reintervention
- Similar risk in both groups
Original publication
Right Heart Reverse Remodeling and Prosthetic Valve Function After Transcatheter vs Surgical Pulmonary Valve Replacement. JACC Cardiovasc Interv. Published 22 January 2024. doi:10.1016/j.jcin.2023.11.030
Summarised from the published abstract; every number is checked against it