Heart failure & cardiomyopathies

Risk Factors of Readmission and the Impact of Outpatient Management in Heart Failure Patients: A National Study in Japan

ESC Heart FailPublished Retrospective cohort study

Authors' conclusion

This study comprehensively identified risk factors for readmission and found outpatient visit is personalized by readmission risk.

Study context

Population
HF patients, Japanese diagnosis-procedure-combination database, April 2016–March 2022analysed
Participants
101,239 patients
Exposure
Outpatient visit frequency after discharge: <1, and >2 visits/month
Outcome
Readmission (risk factors and association with number of outpatient visits)
Follow-up
60 days
Methodological detailsnational administrative database (diagnosis-procedure-combination), multiple logistic regression
  • National administrative database (diagnosis-procedure-combination)
  • Multiple logistic regression

Main finding

As reported in the abstract

60-day readmission
Risk factor: older age
P < 0.001
Risk factor: female
P = 0.009
Risk factor: longer length-of-hospital-stay
P < 0.001
Risk factor: artificial ventilator
P < 0.001
Risk factor: tolvaptan
P < 0.001
Risk factor: top 50% dosage of loop diuretics
P = 0.036
Risk factor: bottom 50% dosage of class III antiarrhythmic agents
P < 0.001
Risk factor: hypertension
P = 0.005
Risk factor: AF
P < 0.001
Risk factor: dilated cardiomyopathy
P < 0.001
Risk factor: valvular disease
P = 0.021
Risk factor: MI
P < 0.001
Risk factor: diabetes
P < 0.001
Risk factor: renal disease
P < 0.001

Observational data: associations, not effects.

Further findings

Readmission risk factors in low- and high-readmission risk subgroups

Possibility that some risk factors are specific to the subgroup

Factors related to frequent outpatient visits (<2 vs (1<, ≦2) visits/month)

Older age
P < 0.001
Home medical care
P = 0.007
Tolvaptan
P < 0.001
Top 50% dosage of loop diuretics
P < 0.001
Diabetes
P < 0.001
Renal disease
P = 0.009
0-2 weeks follow-up
P < 0.001
2-4 weeks follow-up
P < 0.001
Cardiac rehabilitation
P < 0.001
Echocardiography
P < 0.001

Original publication

Risk Factors of Readmission and the Impact of Outpatient Management in Heart Failure Patients: A National Study in Japan. ESC Heart Fail. Published 1 September 2023. doi:10.1002/ehf2.14498

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