Cardio-oncology & otherCohort study
Risk of Cancer After Diagnosis of Cardiovascular Disease
- Retrospective cohort study
- claims database
- time-varying analysis
- multivariable adjustment
Authors' conclusion
Individuals with CVD have an increased risk of developing cancer compared with those without CVD.
Study context
- Population
- Cancer-free individuals with ≥36 months of follow-up data, IBM MarketScan claims data
- Participants
- 27,195,088 individuals
- Exposure
- Cardiovascular disease (CVD) vs no CVD
- Outcome
- Incident cancer
Main finding
As reported in the abstract
Hazard ratio (95% CI)
CVD vs No CVD13% more likely to develop cancer
1.13(1.12–1.13)
aCVD vs No CVD
1.20(1.19–1.21)
aCVD vs Nonatherosclerotic CVD
1.11(1.11–1.12)
Observational data: associations, not effects.
Further findings
Cancer subtypes (atherosclerotic CVD (aCVD))
- Specific associations of aCVD with lung, bladder, liver, colon and other hematologic cancers
Original publication
Risk of Cancer After Diagnosis of Cardiovascular Disease. JACC CardioOncol. Published 11 April 2023. doi:10.1016/j.jaccao.2023.01.010
Summarised from the published abstract; every number is checked against it