Aortic & peripheral vascular disease
Risk of Type B Dissection in Marfan Syndrome: The Cornell Aortic Aneurysm Registry
Authors' conclusion
In our contemporary cohort, type B dissections are more common than type A dissections and occur at traditional nonsurgical thresholds.
Study context
- Population
- Patients with Marfan syndrome in a single-centre registry
- Participants
- 336 patients
- Exposure
- Marfan syndrome (MFS) patients with vs without type B dissection
- Type B dissectionn = 47
- Outcome
- Determinants of type B dissection risk
Methodological detailssingle-centre, registry
- Single-centre
- Registry
Main finding
As reported in the abstract
Elective ARR
P < 0.001
- Type B dissection
- 47 (14%)
- Type A dissection
- 9%
Observational data: associations, not effects.
Further findings
Timing of type B dissection relative to aortic root replacement (ARR)
- Type B dissection after ARR (mean 13.3 years after ARR)
- 55%
- Type B dissection before or without ARR
- 45%
- Aware of MFS diagnosis before type B dissection
- 41 (87%)
Predissection descending aorta size
- Normal or minimally dilated (<4.0 cm), among those with predissection imaging
- 88%
Original publication
Risk of Type B Dissection in Marfan Syndrome: The Cornell Aortic Aneurysm Registry. J Am Coll Cardiol. Published 18 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →