Coronary disease & ACS

Clinical Outcomes of Double-Kissing Crush or Double-Kissing Culotte in Nonleft Main Bifurcation Lesions: The ROUTE Trial

Circ Cardiovasc IntervPublished Observational cohort study

Authors' conclusion

In the present analysis, DK culotte was associated with lower 1-year target lesion failure rates compared with DK crush in true nonleft main coronary artery bifurcations.

Study context

Population
Patients with de novo true non-left main coronary artery bifurcation lesions
Participants
202 patients
Exposure
Double-kissing (DK) culotte vs DK crush
  • DK culotten = 101
  • DK crushn = 101reference
Outcome
Target lesion failure:
  • Target lesion revascularization
  • Target vessel MI
  • Cardiac death
Methodological detailsconsecutive patients
  • Consecutive patients

Main finding

As reported in the abstract

Target lesion failure

P = 0.028

Observational data: associations, not effects.

Secondary outcomes

Target vessel MI (TLF component)

P = 0.651

Cardiac death (TLF component)

P = 0.315

OutcomeDK crushDK culotteP value
Target lesion revascularization (TLF component)9.9%— not stated in the abstractP = 0.045

— not stated in the abstract

All-cause death and definite stent thrombosis

No differences between groups

Original publication

Clinical Outcomes of Double-Kissing Crush or Double-Kissing Culotte in Nonleft Main Bifurcation Lesions: The ROUTE Trial. Circ Cardiovasc Interv. Published 24 October 2024. doi:10.1161/circinterventions.124.014616

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