Heart failure & cardiomyopathies

Rule-based natural language processing to examine variation in worsening heart failure hospitalizations by age, sex, race and ethnicity, and left ventricular ejection fraction

Am Heart JPublished Retrospective cohort study

Authors' conclusion

Rule-based NLP improved the capture of hospitalized WHFE above principal discharge diagnosis codes alone.

Study context

Population
Adult Kaiser Permanente Southern California members with HF diagnosed 2014–2018, followed through 2019
Participants
44,863 members
Exposure
Natural Language Processing (NLP)-defined worsening heart failure events (WHFE) vs HF principal discharge diagnosis codes only
Outcome
Hospitalizations with a principal or secondary HF discharge diagnosis meeting rule-based NLP criteria for WHFE
Methodological detailsrule-based natural language processing
  • Rule-based natural language processing

Main finding

As reported in the abstract

Adjusted WHFE rate (per 100 PY)
Adults with an NLP-defined hospitalized WHFE
10,560 (23.5%)

Observational data: associations, not effects.

Further findings

Adjusted WHFE rate (per 100 person-years (PY)), highest-rate subgroups (NLP vs principal discharge diagnosis)

Adults ≥75 years
16.3 and 11.2
Men
13.2 and 9.7
Non-Hispanic (NH) Black
16.9 and 14.3
Hispanic
15.3 and 11.4
Reduced left ventricular ejection fraction (LVEF)
16.2 and 14.0
NLP disproportionately increased perceived WHFE burden among API and adults with mid-range and preserved LVEF

Original publication

Rule-based natural language processing to examine variation in worsening heart failure hospitalizations by age, sex, race and ethnicity, and left ventricular ejection fraction. Am Heart J. Published 7 September 2024. doi:10.1016/j.ahj.2024.09.001

Composed by AI from the published abstract and checked against it. How Briefs are made →

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