Arrhythmias & electrophysiology
Safety and efficacy of a lattice-tip catheter for ventricular arrhythmia ablation: the AFFERA Ventricular Arrhythmia Ablation Registry (AVAAR)
Authors' conclusion
In this complex population with refractory VA, ablation using the lattice-tip catheter appears feasible and relatively safe.
Study context
- Population
- Patients undergoing ventricular arrhythmia (VA) ablation with a lattice-tip catheter (AFFERA system), European centresVentricular tachycardia (VT) 99, premature ventricular complexes (PVCs) 23, ventricular fibrillation (VF) 4
- Participants
- 126 patients
- Outcome
- Absence of recurrence
- Follow-up
- Mean 5.6 ± 3.7 months
Methodological details18 European centres
- 18 European centres
Main finding
As reported in the abstract
Absence of recurrence, PVC
78%
Absence of recurrence, VT
70%
Absence of recurrence, VF
100%
Observational data: associations, not effects.
Safety
Acute complications
- Major acute complications
- 7 (6%)
- Minor acute complications
- 18 (14%)
- Thrombo-embolic event
- 2
- Major bleeding
- 2
- VF induction
- 1
- Tamponade due to epicardial access
- 1
- Cardiogenic shock due to prolonged VT mapping
- 1
Events within first month post-procedure
- Deaths (multi-organ failure 2, sepsis 1)
- 3
- Worsening HF
- 2
- MI
- 1
- Sepsis
- 1
- Major gastro-intestinal bleeding
- 1
Original publication
Safety and efficacy of a lattice-tip catheter for ventricular arrhythmia ablation: the AFFERA Ventricular Arrhythmia Ablation Registry (AVAAR). Europace. Published 2 July 2025. doi:10.
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