Arrhythmias & electrophysiology
A novel focal lattice-tip catheter toggling between pulsed field energy and radiofrequency for atrial arrhythmia ablation: Results from a real-world, multicenter registry
Authors' conclusion
Catheter ablation with a novel 9-mm lattice-tip catheter confirmed high efficacy and safety in a real-world scenario.
Study context
- Population
- Consecutive AF patients undergoing first-time or redo atrial tachyarrhythmia ablation with the Affera focal lattice-tip catheter at 3 centres
- Participants
- 130 patients
- Exposure
- Pulsed field (PF)/radiofrequency (RF) vs PF/PF
- Outcome
- Acute electrical isolation of pulmonary veins and posterior wall, or bidirectional block for linear lesions
Methodological detailsreal-world, consecutive enrolment
- Real-world
- Consecutive enrolment
Main finding
As reported in the abstract
Primary efficacy end point
Primary efficacy end point
100%
First-pass isolation (all ablation lines)
96.2%
First-pass isolation, pulmonary vein and posterior wall (first-time PVI, n = 72)
100%
Observational data: associations, not effects.
Further findings
First-pass isolation by ablation line (289 lines)
- Roof line (91 patients)
- 100%
- Inferior line (83 patients)
- 100%
- Anterior mitral line (32 patients)
- 96.9%
- Posterior mitral line (45 patients)
- 84.4%
- Cavotricuspid isthmus line (38 patients)
- 92.1%
Safety
Major complications
- Major complications
- 2 (1.5%)
- ST-segment elevation at inferolateral leads requiring intracoronary nitrate
- 1
- Complete atrioventricular block
- 1
Original publication
A novel focal lattice-tip catheter toggling between pulsed field energy and radiofrequency for atrial arrhythmia ablation: Results from a real-world, multicenter registry. Heart Rhythm. Published 16 December 2024. doi:10.
Summarised from the published abstract; every number is checked against it