Arrhythmias & electrophysiology
Safety and efficacy of intracardiac echocardiography–guided zero-fluoroscopic cryoballoon ablation for atrial fibrillation: a prospective randomized controlled trial
Authors' conclusion
Intracardiac echocardiography-guided fluoroless CBA for AF was a feasible strategy without compromising acute and long-term success or complication rates.
Study context
- Population
- Patients undergoing cryoballoon ablation for paroxysmal atrial fibrillation (AF), with intracardiac echocardiography (ICE) guidance in all
- Participants
- 100 patients
- Comparison
- ICE-guided zero-fluoroscopic cryoballoon ablation (CBA) vs conventional CBA
Methodological detailsprospective, 12-month prospective follow-up after CBA
- Prospective
- 12-month prospective follow-up after CBA
Primary result
As reported in the abstract
Fluoroscopic time and radiation exposure
| Group | Fluoroscopic time | Radiation exposure |
|---|---|---|
| Zero-X | 0.008 min | 0.02 mGy |
| Conventional | 9.0 min | 29.4 mGy |
Fluoroscopic time
Zero-X0.008 min
Conventional9.0 min
Radiation exposure
Zero-X0.02 mGy
Conventional29.4 mGy
- Zero-X vs Conventional: P < 0.001 — fluoroscopic time and radiation exposure significantly shorter with Zero-X
Further findings
Acute pulmonary vein isolation (PVI)
- PVI achieved in all patients
Procedure time and left atrial (LA) indwelling time
- Not statistically different between groups
AF recurrence · mean follow-up 663.3 ± 172.3 days
- Recurrence rate similar between the groups (16.0 vs. 18.0%)
- P = 0.841
Predictors of clinical recurrence (multivariate)
- LA size the only independent predictor
Safety
- Complication rate did not differ between the two groups
Original publication
Safety and efficacy of intracardiac echocardiography–guided zero-fluoroscopic cryoballoon ablation for atrial fibrillation: a prospective randomized controlled trial. Europace. Published 6 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →