Arrhythmias & electrophysiology

Systematic Workflow and Electrogram guidance to reduce X-ray Exposure Time during cryoballoon ablation of atrial fibrillation: the SWEET-Cryo strategy

EuropacePublished Prospective cohort study with retrospective control cohort

Authors' conclusion

In contrast to conventional protocols and regardless of the operator's experience, the optimized SWEET-Cryo strategy dramatically reduced fluoroscopy exposure during CB-PVI.

Study context

Population
Patients with paroxysmal or persistent atrial fibrillation (AF) undergoing cryoballoon pulmonary vein isolation
Participants
100 patients
Exposure
SWEET-Cryo strategy vs conventional fluoroscopy during cryoballoon pulmonary vein isolation (CB-PVI)
  • SWEET-Cryon = 50
  • Conventional fluoroscopyn = 50reference
Outcome
Fluoroscopy time and dose area product
Methodological detailstwo operators with different levels of expertise
  • Two operators with different levels of expertise

Main finding

As reported in the abstract

Fluoroscopy time, senior operator
GroupValueDose area product (DAP) (Gy cm²)
SWEET-Cryomean 2.6 (SD 1.25) min5.1 ± 3.8
Conventional fluoroscopymean 20.3 (SD 10.8) min35.3 ± 22.3

Value

SWEET-Cryomean 2.6 (SD 1.25) min
Conventional fluoroscopymean 20.3 (SD 10.8) min

Dose area product (DAP) (Gy cm²)

SWEET-Cryo5.1 ± 3.8
Conventional fluoroscopy35.3 ± 22.3
  • SWEET-Cryo vs Conventional fluoroscopy: P < 0.001 — fluoroscopy time (FT) and DAP

Observational data: associations, not effects.

Further findings

FT and DAP, less experienced operator

Significant reduction in FT with SWEET-Cryo vs control: 6.4 ± 2.5 min vs 32.5 ± 10.05
P < 0.001
Significant reduction in DAP with SWEET-Cryo vs control: 13.9 ± 7.7 vs 92.3 ± 63.8
P < 0.001

Freedom from AF · 33-month median follow-up

No difference between fluoroscopy strategies

Mean FT in randomly selected cases during follow-up

Mean FT maintained below 3 min

Safety

Acute and long-term complications · 33-month median follow-up

No difference between fluoroscopy strategies

Original publication

Systematic Workflow and Electrogram guidance to reduce X-ray Exposure Time during cryoballoon ablation of atrial fibrillation: the SWEET-Cryo strategy. Europace. Published 27 July 2023. doi:10.1093/europace/euad231

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